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Liang Hong

Postdoctoral Research Associate

Center for Molecular Biophysics
Building 6011, Oak Ridge National Laboratory

Oak ridge , TN 37830


  1. Ph.D., Polymer Science, The University of Akron 2010
  2. MS., Physics, Chinese University of Hong Kong 2006
  3. BS., Physics, University of Sci.and Tech. of China 2004



Protein dynamics, structure and function, studied using Molecular Dynamics Simulation and Neutron, Light scattering.

Dynamics of glass-forming materials, especially polymers.


21. L. Hong, M. Sharp, S. Poblete, R. Bhiel, X. Cheng, D. Richter and J. C. Smith “Detailed structure and dynamics of a compact state of a multidomain protein, the mercuric ion reductase, in aqueous solution”,  Biophys. J.  , in press.

20. L. Hong, L. Petridis and J. C. Smith “Biomolecular Structure and Dynamics with Neutrons: The View from Simulation.”, Isr. J. Chem.,  in press.

19. L. Hong,N. Smolinand J. C. Smith “De Gennes Narrowing Describes the Relative Motion of Protein Domains”, Phys. Rev. Lett., 112, 158102 (2014).

18. Y. Miao, L. Hong, Z. Yi and J. C. Smith “Zaccai Resilience and Site-specific Hydration in a Globular Protein”, The European Physical Journal E, 36, 9885 (2013). 

17. L. Hong, D.C. Glass, J.D. Nickels, S. Perticaroli, Z. Yi, T. Madhusudan, H. O’Neill, Q. Zhang, A. P. Sokolov and J.C. Smith “Elastic and conformational softness of a globular protein”, Phys. Rev. Lett., 110, 028104 (2013).

16. Y.L. Miao, Z. Yi, D.C. Glass, L. Hong, M. Tyagi, J. Baudry, N. Jain and J.C. Smith. "Temperature-dependent Dynamical Transitions of Different Classes of Amino Acid Residue in a Globular Protein", J. Am. Chem. Soc. 134, 19576 (2012).

15. J.D. Nickels, H. O’Neill, L. Hong, M. Tyagi, G. Ehlers, K. Weiss, Q. Zhang, Z. Yi, E. Mamontov, J.C. Smith and A.P. Sokolov. “Dynamics of Protein and its Hydration Water: Neutron Scattering Studies on Fully Deuterated GFP”, Biophys. J.  103, 1566 (2012).

14. L. Hong, X. Cheng, D.C. Glass, and J.C. Smith. “Surface hydration amplifies single-well protein atom diffusion propagating into the macromolecular core”,  Phys. Rev. Lett., 108, 238102 (2012).

13. L. Hong, N. Smolin, B. Lindner, A.P. Sokolov, and J.C. Smith. “Three classes of motion in the dynamic neutron scattering susceptibility of a globular protein”, Phys. Rev. Lett., 107, 148102 (2011).

12. L. Hong, V.N. Novikov, and A.P. Sokolov. “Dynamic  heterogeneities, boson peak, and activation volume in glass-forming liquids”, Phys. Rev. E, 83, 061508 (2011).

11. L. Hong, V.N. Novikov, and A.P. Sokolov. “Is there any connection between fragility of glass forming systems and dynamic heterogeneity /cooperativity?”, J. Non-Cryst. Solids, 357, 351 (2011).

10. L. Hong, B. Begen, A. Kisliuk, V.N. Novikov, and A.P. Sokolov. “Influence of pressure on fast picosecond relaxation in glass-forming materials”, Phys. Rev. B, 81, 104207 (2010).

9.  L. Hong, P.D. Gujrati, V.N. Novikov, and A.P. Sokolov. “Molecular cooperativity in the dynamics of glass-forming systems: A new insight”, J. Chem. Phys., 131, 194511 (2009).

8.  L. Hong, B. Begen, A. Kisliuk, S. Pawlus, M. Paluch, and A.P. Sokolov. “Influence of pressure on quasielastic scattering in glasses: Relationship to the boson peak”, Phys. Rev. Lett., 102, 145502 (2009).

7.  L. Hong, B. Begen, A. Kisliuk, C. Alba-Simionesco, V.N. Novikov, and A.P Sokolov. “Pressure and density dependence of the boson peak in polymers”, Phys. Rev. B, 78,134201 (2008).

6.  G. Carini Jr, G. Carini, G. D’Angelo, G. Tripodo, A. Bartolotta, G. Salvato, and L. Hong. “Low temperature Specific heat of heterocyclic polymer networks: Effect of network density”, Phil. Mag., 88, 3999 (2008).

5.  S. Pawlus, K. Kunal, L. Hong, and A.P. Sokolov. “Influence of molecular weight on dynamic crossover temperature in linear polymers”, Polymer, 49, 2918 (2008).

4. L. Hong, Z. Liu, X.T. Zhang, and S.K. Hark. “Self-catalytic growth of single-phase AlGaN alloy nanowires by chemical vapor deposition”, Appl. Phys. Lett., 89, 193105 (2006).

3. L. Hong, Z.R. Wang, and S.K. Hark. “Relationship of the SERRS of CV and the concentration of Ag colloids”, Chin. J. Light Scattering, 18, 21 (2006).

2. X.D. Meng, B.X. Lin, L. Hong, J.J. Zhu, X.K. Sun, J. Xu, and Z.X. Fu. “Photoluminescence Properties for ZnO Films Grown by Two-step CVD”, Chin. J. Lumin., 27, 792 (2006).

1. G.L. Zhao, B.X. Lin, L. Hong, X.D. Meng, and Z.X. Fu. “Structural and luminescent properties of ZnO thin films deposited by atmospheric pressure chemical vapor deposition”, Chin. Phys. Lett., 21, 1381 (2004).