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Sambit Mishra

Postdoctoral Research Associate

Email: mishras@ornl.gov
 

Address:
E340, Bldg. 2040
1 Bethel Valley Rd.
Oak Ridge, TN 37831-6309

Websites

 

Google Scholar: https://scholar.google.com/citations?user=ShTa3q4AAAAJ&hl=en&oi=ao

ResearchGate: https://www.researchgate.net/profile/Sambit_Mishra6

LinkedIn: https://www.linkedin.com/in/sambit-mishra-75b04024

Education / Biography

 

Ph.D. in Bioinformatics and Computational Biology, Iowa State University, 2012-2018

B.S. in Bioinformatics, Bharath Institute of Higher Education and Research, 2003-2007

 

 

Research Interests

 

  • Probing protein functional dynamics using elastic network models

  • Understanding Allosteric regulation in proteins

  • Using machine learning to identify regulatory and active site residues in proteins 

  • Inter-residue co-evolution and its applications to understanding protein-protein interactions

Publications

 

  • Mishra SK, Jernigan RL (2018) Protein dynamic communities from elastic network models align closely to the communities defined by molecular dynamics. PLOS ONE 13(6): e0199225. https://doi.org/10.1371/journal.pone.0199225
  • Sankar K, Mishra SK and Jernigan RL (2018) Comparisons of Protein Dynamics from Experimental Structure Ensembles, Molecular Dynamics Ensembles, and Coarse-Grained Elastic Network Models. The Journal of Physical Chemistry B 2018 122 (21), 5409-5417 DOI: 10.1021/acs.jpcb.7b11668
  • Mishra, SK., Sankar, K and Jernigan, RL. (2017), Altered dynamics upon oligomerization corresponds to key functional sites. Proteins, 85: 1422-1434. https://doi.org/10.1002/prot.25302

 

 
 
 

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