Education / Biography
Ph.D. in Chemical Engineering, University of Tennessee, Knoxville, 2012-2017
B.S. in Chemical Engineering, Marathwada University, India
- Development of a broadly protective vaccine against Group A Strep
- Functional Nanomaterials
TiO2 is a transition metal oxide and finds applications in pigments, additives, catalysts and construction materials. However, some experimental studies have uncovered the potential cytotoxic effects of transition metal oxide nanoparticles which include changes in cell morphology, mitochondrial functions, membrane leakage, necrosis and apoptosis. With their extensive use in a wide array of applications it has become of vital importance to understand their potential cytotoxic effect to design them for safe applications. Molecular dynamics (MD) simulations can help shed some light on the nature of the interaction when the metal oxide nanoparticle first encounters the cell membrane. Through atomistic MD study, we assess the effect of the TiO2 nanoparticle on the structural, mechanical and dynamical properties of neutral DOPC and charged DOPG bilayers. These preliminary studies pave the way for a more detailed study into the differential interactions of various other metal oxide nanoparticles with mixed lipid bilayers.
- Peptide – MHC binding prediction for cancer vaccine development
- Ion transport through nanopores