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Education / Biography

Doctor of Philosophy, Physics, Drexel University, June 2014

Dissertation Title “Influence of aqueous-salt conditions on the structure and dynamics of the monomeric and novel dimeric forms of the Alzheimer’s Aβ21-30 Protein Fragment”

M.S. Physics, Drexel University, June 2011

B.S. Physics, Portland State University (University Honor’s College/Program), June 2009

Research Interests

Prof. Smith is a Research Assistant Professor with the Department of Biochemistry and Cellular and Molecular Biology at The University of Tennessee, Knoxville and member of the UT/ORNL Center for Molecular Biophysics. Prof. Smith’s work makes use of physics and machine-learning based computational modelling techniques to probe chemical and biophysical systems ranging from small organic molecules to large-multi-biopolymer complexes.  In collaboration with members within the UT/ORNL CenterHis most recent research efforts have been divided between: (1) Probing microbial biomembranes and their robustness to organic solvents and embedded small-molecules; (2) Generating molecular models of plant cell walls and cell wall components under industrially relevant pretreatment and upgrading conditions to advance biofuels and bioproduct development; (3) High performance virtual screening techniques for small molecule drug discovery; (4) Exploring the antifreeze peptide structure-function relationships. A complete list of Prof. Smith’s work is available at: https://faculty.utk.edu/Micholas.Smith/ and https://orcid.org/0000-0002-0777-7539

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